Antibiotic therapy affects functional behaviour in cystic fibrosis blood mononuclear cells.
نویسندگان
چکیده
Cystic fibrosis (CF) is the most common life-shortening genetic disorder in the Caucasian population and is due to mutations at the CF transmembrane conductance regulator (CFTR) gene leading to dysfunction of the protein, which normally acts as a chloride channel. This basic defect is associated with a progressive and lethal lung disease [1]. Opportunistic respiratory infections are common in CF patients’ lungs, making antibiotics an important part of the regular care.
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ورودعنوان ژورنال:
- The European respiratory journal
دوره 46 2 شماره
صفحات -
تاریخ انتشار 2015